Dr. Ngozi Ugochukwu is a professor of Biochemistry.The main thrust of our research
is the use of enzymology and cutting-edge biochemical and gene technology techniques
in deciphering the underlying mechanisms in the pathophysiology of chronic metabolic
diseases especially diabetes, obesity, congestive heart failure and colon cancer and
their unifying link in quest of non-invasive nutritional interventions for effective
preventive strategies and therapies. The methodologies are multifaceted involving
the ‘omics’: pharmaco/nutrigenomics; transcriptomics (examining the expression level
of mRNAs using high thorough-put techniques based on DNA microarray technology); proteomics
(in discovery of disease biomarkers) and metabolomics (end-products of gene expression).
Integration of all the data obtained from these methodologies give a more complete
picture of the status of the organism in the disease state and therefore very valuable
at the molecular level.
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